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P-gp

Anti-P-gp Products

Recombinant Mouse Anti-P-glycoprotein Antibody (C219) (PABC-102)
- Derivation: Mouse
- Type: IgG
- Application: WB
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Recombinant Mouse Anti-P-glycoprotein Antibody (MRK-16) (PABZ-102)
- Derivation: Mouse
- Type: IgG
- Application: WB, IHC, IF, FuncS
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Mouse Anti-P-gp Antibody (clone MRK-16), mRNA (PABZ-102-mRNA)
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Recombinant Mouse Anti-P-glycoprotein Antibody Fab Fragment (C219) (PFBC-102)
- Derivation: Mouse
- Type: IgG
- Application: WB
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Recombinant Mouse Anti-P-glycoprotein Antibody Fab Fragment (MRK-16) (PFBZ-102)
- Derivation: Mouse
- Type: IgG
- Application: WB, IHC, IF, FuncS
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Recombinant Mouse Anti-P-glycoprotein Antibody scFv Fragment (C219) (PSBC-102)
- Derivation: Mouse
- Type: scFv
- Application: WB
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Recombinant Mouse Anti-P-glycoprotein Antibody scFv Fragment (MRK-16) (PSBZ-102)
- Derivation: Mouse
- Type: scFv
- Application: WB, IHC, IF, FuncS
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For Research Use Only. Not For Clinical Use.

Background

P-glycoprotein 1 (permeability glycoprotein, abbreviated as P-gp or Pgp) also known as multidrug resistance protein 1 (MDR1) or ATP-binding cassette sub-family B member 1 (ABCB1) or cluster of differentiation 243 (CD243) is an important protein of the cell membrane that pumps many foreign substances out of cells. More formally, it is an ATP-dependent efflux pump with broad substrate specificity. It exists in animals, fungi and bacteria and likely evolved as a defense mechanism against harmful substances.