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PHACTR3
Anti-PHACTR3 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the phosphatase and actin regulator protein family. The encoded protein is associated with the nuclear scaffold in proliferating cells, and binds to actin and the catalytic subunit of protein phosphatase-1, suggesting that it functions as a regulatory subunit of protein phosphatase-1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Oligodendrocytes, Oligodendrocyte precursor cells, Astrocytes, Excitatory neurons, Inhibitory neurons)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (CAPAN-2, HBEC3-KT, PC-3, THP-1, U-937)
Interaction
Binds actin and PPP1CA; thus inhibiting the protein phosphatase 1 (PP1) activity.
Molecular function
Actin-binding, Protein phosphatase inhibitor
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