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PRDM16
Anti-PRDM16 Recombinant Antibody Products
- Anti-PRDM16 Immunohistochemistry Kit (VS-0325-XY1733)
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- Species Reactivity: Human, Mouse, Rat
- Target: PRDM16
- Application: IHC
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For Research Use Only. Not For Clinical Use.
The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain.