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PRMT6

Anti-PRMT6 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


PRMT6 is a protein arginine N-methyltransferase, and catalyzes the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation is a prevalent post-translational modification in eukaryotic cells that has been implicated in signal transduction, the metabolism of nascent pre-RNA, and the transcriptional activation processes.
Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enriched (MCF7)

Interaction

Interacts with EPB41L3 and NCOA1. (Microbial infection) Interacts with (and methylates) HIV-1 Tat, Rev and Nucleocapsid protein p7 (NC). (Microbial infection) Interacts with human cytomegalovirus protein UL69.

Molecular function

Chromatin regulator, Methyltransferase, Repressor, Transferase

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