RECQL

Recombinant Antibody Products

Anti-RECQL Recombinant Antibody Products

Hi-Affi™ Recombinant Rabbit Anti-RECQL Monoclonal Antibody (DS3038AB) (MOR-3038)
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.

The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. Some members of this family are associated with genetic disorders with predisposition to malignancy and chromosomal instability. The biological function of this helicase has not yet been determined. Two alternatively spliced transcripts, which encode the same isoform but differ in their 5' and 3' UTRs, have been described.

Protein class

Enzymes, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Interacts with EXO1 (PubMed:15886194). Interacts with MLH1.

Molecular function

DNA-binding, Helicase, Hydrolase

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