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RGS20
Anti-RGS20 Recombinant Antibody Products
- Recombinant Mouse Anti-Human RGS20 Antibody (MOB-1643MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA, WB
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Astrocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (GAMG, SK-MEL-30, U-87 MG)
Interaction
Forms a complex with G(alpha)z/i2 subunits and mu-opioid receptors; the formation of this complex results in mu-opioid receptor desensitization. Interacts with OPRM1 (By similarity).
Molecular function
Signal transduction inhibitor
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