SERPINB1

Antibody Magnetic Beads AbPlus Recombinant Antibody Products Formats

Anti-SERPINB1 Recombinant Antibody Products

AbPlus™ Anti-SERPINB1 Magnetic Beads (VS-0724-YC879) (VS-0724-YC879)
- Target: SERPINB1
- Target Species: Human
- Application: IP, Protein Purification
Compare

Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

More Infomation

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

For Research Use Only. Not For Clinical Use.

The protein encoded by this gene is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants.

Protein class

Plasma proteins

Predicted location

Intracellular, Secreted (different isoforms)

Single cell type specificity

Cell type enhanced (Exocrine glandular cells, Pancreatic endocrine cells, Urothelial cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (CAPAN-2, OE19, U-937)

Interaction

Monomer (PubMed:23269243). Interacts (via C-terminus) with CASP1; CASP4 (via CARD domain) and CASP5; these interactions regulate the activity of inflammatory caspases (PubMed:30692621). Interacts with PRTN3 (PubMed:30692621). Interacts with GZMH (PubMed:23269243).

Molecular function

Protease inhibitor, Serine protease inhibitor

More Types Infomation