SIGIRR

Recombinant Antibody Products Formats

Anti-SIGIRR Recombinant Antibody Products

Recombinant Mouse anti-Human SIGIRR Monoclonal antibody (NN0658-20E6) (MOB-1374CT)
- Species Reactivity: Human
- Application: WB
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For Research Use Only. Not For Clinical Use.

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Proximal tubular cells, Hepatocytes)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (CAPAN-2, MCF7)

Interaction

Interacts with IL1R1, IRAK1, TLR4, TLR5, TLR9 and TRAF6. Upon IL-1 stimulation found in a complex at least composed of IL1R1, SIGIRR, MYD88, IRAK1 and TRAF6. Upon stimulation with LPC found in a complex at least composed of TLR4, SIG1IR, MYD88, IRAK1 and TRAF6. Interacts with PALM3.

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