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SIGLEC11
Anti-SIGLEC11 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. This family member mediates anti-inflammatory and immunosuppressive signaling. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein class
Plasma proteins
Predicted location
Membrane
Single cell type specificity
Group enriched (Granulosa cells, Theca cells)
Immune cell specificity
Immune cell enhanced (eosinophil, non-classical monocyte)
Cell line specificity
Cell line enriched (HEL)
Interaction
Interacts with PTPN6/SHP-1 and PTPN11/SHP-2 upon phosphorylation.
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