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SLITRK6
This gene encodes a member of the SLITRK protein family. Members of this family are integral membrane proteins that are characterized by two N-terminal leucine-rich repeat (LRR) domains and a C-terminal region that shares homology with trk neurotrophin receptors. This protein functions as a regulator of neurite outgrowth required for normal hearing and vision. Mutations in this gene are a cause of myopia and deafness. [provided by RefSeq, Dec 2014]
Protein class
Disease related genes, Human disease related genes
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Bipolar cells, Respiratory ciliated cells, Club cells, Basal respiratory cells, Ionocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (hTCEpi, OE19, RT4, WM-115)
More Types Infomation
- Anti-SLITRK6-MMAE ADC (ADC-040LZY)
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- Target: SLITRK6
- Linker: cleavable linker
- Drug: MMAE (monomethyl auristatin E)
- Anti-SLITRK6 (AGS15)-mc-vc-MMAE ADC (ADC-156LCT)
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- Target: SLITRK6
- Linker: mc-VC (maleimidocaproyl-valine-citrulline)
- Drug: MMAE (Monomethyl auristatin E)
- Recombinant Human Anti-SLITRK6 Antibody (clone Sirtratumab) (VS-0923-FY258)
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- Species Reactivity: Human
- Type: Human IgG2, kappa
- Application: ELISA, WB
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For Research Use Only. Not For Clinical Use.