Enzymes, Metabolic proteins
Intracellular
Cell type enhanced (Ductal cells, Hepatocytes)
Low immune cell specificity
Cell line enhanced (HHSteC, hTCEpi, hTERT-HME1, SK-MEL-30)
Interacts with AKT1, AKT2, MAP2K1 and MAP2K7 (PubMed:15299019). Interacts with ATF4 (PubMed:12743605). Interacts with DDIT3/CHOP and inhibits its interaction with EP300/P300 (PubMed:15775988, PubMed:17872950). Interacts with APOBEC3C (PubMed:22977230). Interacts (via N-terminus) with APOBEC3A (PubMed:22977230). Interacts with RELA (PubMed:12736262).
Protein kinase inhibitor
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For Research Use Only. Not For Clinical Use.