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TRIM35
Anti-TRIM35 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified. [provided by RefSeq, Jul 2008]
Protein class
Enzymes
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Basal squamous epithelial cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (ASC diff)
Interaction
Interacts with PKM isoform M2, but not isoform M1; this interaction may compete with that between PKM and FGFR1, and hence reduces FGFR1-dependent tyrosine phosphorylation of PKM (PubMed:25263439). Interacts with IRF7; this interaction promotes IRF7 proteasomal degradation (PubMed:25907537). Interacts with TRAF3; this interaction promotes TRAF3 activation (PubMed:32562145).
Molecular function
Transferase
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