TWF1

AbPlus Formats

Anti-TWF1 Recombinant Antibody Products

Anti-TWF1 Immunohistochemistry Kit (VS-0325-XY2395)
- Species Reactivity: Human, Mouse, Rat
- Target: TWF1
- Application: IHC
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For Research Use Only. Not For Clinical Use.

This gene encodes twinfilin, an actin monomer-binding protein conserved from yeast to mammals. Studies of the mouse counterpart suggest that this protein may be an actin monomer-binding protein, and its localization to cortical G-actin-rich structures may be regulated by the small GTPase RAC1.

Protein class

Disease related genes

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Interacts with G-actin; ADP-actin form and capping protein (CP). May also be able to interact with TWF2 and phosphoinositides, PI(4,5)P2. When bound to PI(4,5)P2, it is down-regulated (By similarity). Interacts with ACTG1 (PubMed:28493397).

Molecular function

Actin-binding

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