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TcdB

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For Research Use Only. Not For Clinical Use.


Background

Clostridium difficile is a Gram-positive bacterium that causes antibiotic-associated diarrhea and colitis. TcdB is one of the two major toxins produced by C. difficile. It is a glucosyltransferase that disrupts the actin cytoskeleton of host cells, leading to cell death and inflammation. TcdB is a potential target for vaccine development.
TcdB
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