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V antigen
Anti-V antigen Recombinant Antibody Products
- Human Anti-V antigen Recombinant Antibody (HPAB-AP843-YC) (HPAB-AP843-YC)
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- Species Reactivity: Y. pestis
- Type: Human IgG
- Application: ELISA, FuncS
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- Human Anti-V antigen Recombinant Antibody (HPAB-AP844-YC) (HPAB-AP844-YC)
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- Species Reactivity: Y. pestis
- Type: Human IgG
- Application: ELISA, FuncS
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- Human Anti-V antigen Recombinant Antibody; scFv Fragment (HPAB-AP843-YC-S(P)) (HPAB-AP843-YC-S(P))
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- Species Reactivity: Y. pestis
- Type: Human scFv
- Application: ELISA
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- Human Anti-V antigen Recombinant Antibody; scFv Fragment (HPAB-AP844-YC-S(P)) (HPAB-AP844-YC-S(P))
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- Species Reactivity: Y. pestis
- Type: Human scFv
- Application: ELISA
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- Human Anti-V antigen Recombinant Antibody; Fab Fragment (HPAB-AP843-YC--F(E)) (HPAB-AP843-YC--F(E))
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- Species Reactivity: Y. pestis
- Type: Human Fab
- Application: ELISA
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- Human Anti-V antigen Recombinant Antibody; Fab Fragment (HPAB-AP844-YC--F(E)) (HPAB-AP844-YC--F(E))
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- Species Reactivity: Y. pestis
- Type: Human Fab
- Application: ELISA
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For Research Use Only. Not For Clinical Use.
Yersinia pestis, the etiologic agent of plague, secretes a set of environmentally regulated, plasmid pCD1-encoded virulence proteins termed Yops and V antigen (LcrV) by a type III secretion mechanism (Ysc). LcrV is a multifunctional protein that has been shown to act at the level of secretion control by binding the Ysc inner-gate protein LcrG and to modulate the host immune response by altering cytokine production. LcrV also is essential for the unidirectional targeting of Yops to the cytosol of infected eukaryotic cells.