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WNT10B
Anti-WNT10B Recombinant Antibody Products
- Mouse Anti-WNT10B Recombinant Antibody (clone 5A7) (VS3-QX1245)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, ICC, FC, ELISA
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- Mouse Anti-WNT10B Monoclonal Antibody (VS7-0425-WR1131) (VS7-0425-WR1131)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC-P, IF, ICC, ELISA
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For Research Use Only. Not For Clinical Use.
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is likely a molecular switch that governs adipogenesis. This protein is 96% identical to the mouse Wnt10b protein at the amino acid level. This gene is clustered with another family member, WNT1, in the chromosome 12q13 region. [provided by RefSeq, Jul 2008]
Protein class
Disease related genes, Human disease related genes
Predicted location
Secreted
Single cell type specificity
Cell type enhanced (Extravillous trophoblasts, Excitatory neurons, Fibroblasts, Inhibitory neurons)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (K-562, T-47d, U-266/84)
Interaction
Forms a soluble 1:1 complex with AFM; this prevents oligomerization and is required for prolonged biological activity (PubMed:26902720). The complex with AFM may represent the physiological form in body fluids (PubMed:26902720).
Molecular function
Developmental protein
More Types Infomation
Related Signaling Pathways
Canonical Wnt Signaling Pathway
mTOR Signaling Pathway
Non-Canonical Wnt Signaling Pathway
Related Diseases
Throid Cancer
Cushing Syndrome