Recombinant monoclonal antibody specifically binds to and neutralizes the protective antigen of Bacillus anthraci. Antibody 33F4 is specific for epitopes resideing in the PA20 domain of the PA molecule.
Figure 1 Dot blot assay of representative CHO cell-derived IgG1 PA-specific human monoclonal antibodies.
PA83 and PA63 were purchased from List Biological Laboratories. D4-GFP and PA20-GFP were expressed and purified from E. coli as described in the materials and methods section. All antigens were spotted at 1 µg per spot using a 96 well manifold. Blots were cut into strips and probed with individual PA-specific monoclonal antibodies.
Reason, D. C., Ullal, A., Liberato, J., Sun, J., Keitel, W., & Zhou, J. (2008). Domain specificity of the human antibody response to Bacillus anthracis protective antigen. Vaccine, 26(32), 4041-4047.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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MRO-090CT-S(P) | Anti-B. anthracis toxin Recombinant Antibody scFv Fragment (1A5) | ELISA, WB, Neut | Human antibody |
MRO-091CT-S(P) | Anti-B. anthracis toxin Recombinant Antibody scFv Fragment (4A12) | ELISA, WB, Neut | Human antibody |
MRO-092CT-S(P) | Anti-B. anthracis toxin Recombinant Antibody scFv Fragment (24B1) | ELISA, WB, Neut | Human antibody |
MRO-093CT-S(P) | Anti-B. anthracis toxin Recombinant Antibody scFv Fragment (24G4) | ELISA, WB, Neut | Human antibody |
MRO-094CT-S(P) | Anti-B. anthracis toxin Recombinant Antibody scFv Fragment (33F4) | ELISA, WB, Neut | Human antibody |
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