Anti-B. anthracis toxin Recombinant Antibody (33F4) (CAT#: MRO-094CT)

Recombinant monoclonal antibody specifically binds to and neutralizes the protective antigen of Bacillus anthraci. Antibody 33F4 is specific for epitopes resideing in the PA20 domain of the PA molecule.


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DB

Figure 1 Dot blot assay of representative CHO cell-derived IgG1 PA-specific human monoclonal antibodies.

Figure 1 Dot blot assay of representative CHO cell-derived IgG1 PA-specific human monoclonal antibodies.

PA83 and PA63 were purchased from List Biological Laboratories. D4-GFP and PA20-GFP were expressed and purified from E. coli as described in the materials and methods section. All antigens were spotted at 1 µg per spot using a 96 well manifold. Blots were cut into strips and probed with individual PA-specific monoclonal antibodies.

Reason, D. C., Ullal, A., Liberato, J., Sun, J., Keitel, W., & Zhou, J. (2008). Domain specificity of the human antibody response to Bacillus anthracis protective antigen. Vaccine, 26(32), 4041-4047.


Specifications

  • Immunogen
  • PA protein of B. anthracis
  • Host Species
  • Human
  • Type
  • Human antibody
  • Specificity
  • B. anthracis
  • Species Reactivity
  • B. anthracis
  • Clone
  • 33F4
  • Applications
  • ELISA, WB, Neut, DB
  • Related Disease
  • Anthrax (Bacillus anthracis)

Applications

  • Application Notes
  • The B. anthracis toxin antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Western Blot, Neutralization, Dot Blot.

Target

  • Alternative Names
  • Bacillus anthracis toxin; Anthrax toxin; Bacillus anthracis; B. anthracis

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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Human Antibody

CAT Product Name Application Type
MRO-090CT Anti-B. anthracis toxin Recombinant Antibody (1A5) Neut, ELISA, Cyt, Funcs, WB Human antibody
MRO-091CT Anti-B. anthracis toxin Recombinant Antibody (4A12) Neut, ELISA, Cyt, DB, WB Human antibody
MRO-092CT Anti-B. anthracis toxin Recombinant Antibody (24B1) Neut, ELISA, Cyt, DB, Inhib, WB Human antibody
MRO-090CT-F(E) Anti-B. anthracis toxin Recombinant Antibody Fab Fragment (1A5) ELISA, WB, Neut Human antibody
MRO-091CT-F(E) Anti-B. anthracis toxin Recombinant Antibody Fab Fragment (4A12) ELISA, WB, Neut Human antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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