Afuco™ Anti-Human CDK5R1 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-146CL)
Anti-CDK5R1 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. This is a monoclonal antibody binds specifically to the cyclin-dependent kinase 5 (Cdk5) activating protein, p25 and not to p35, a hybridoma cell line producing the monoclonal antibody, and the use of the monoclonal antibody is for detection and treatment of neuronal disorders and cancers.
Specific Inquiry
Subcellular Location and Protein Expression
RNA Expression
Figure 1 IF staining of human cell line SH-SY5Y
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/252/if_selected.jpg
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/252/if_selected.jpg
Figure 2 RNA cell line category: Group enriched (SCLC-21H, SH-SY5Y, SK-MEL-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000176749-CDK5R1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000176749-CDK5R1
Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >95%, by SDS-PAGE with Coomassie Brilliant Blue staining
- Storage
- ≤1 year at -20°C.
Target
- Alternative Names
- CDK5R1; cyclin-dependent kinase 5, regulatory subunit 1 (p35); p23; p25; p35; CDK5R; NCK5A; CDK5P35; p35nck5a; cyclin-dependent kinase 5 activator 1; CDK5 activator 1; neuronal CDK5 activator; TPKII regulatory subunit; regulatory partner for CDK5 kinase; tau protein kinase II 23kDa subunit; cyclin-dependent kinase 5 regulatory subunit 1
- Gene ID
- 8851
- UniProt ID
- Q15078
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CDK5R1"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-530-sdAb | Recombinant Anti-Human CDK5R1 VHH Single Domain Antibody | Neut, ChiP, IP, FUNC | Llama VHH |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2461z | Mouse Anti-CDK5R1 Recombinant Antibody (clone 21G11) | WB, ELISA, IF, IP | Mouse IgG2a, κ |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-407LC | Anti-Human CDK5R1 Recombinant Antibody (1C4) | ELISA | |
| TAB-407LC-S(P) | Anti-Human CDK5R1 Recombinant Antibody scFv Fragment (1C4) | ELISA | |
| TAB-407LC-F(E) | Anti-Human CDK5R1 Recombinant Antibody Fab Fragment (1C4) | ELISA |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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