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Urtoxazumab (TAB-157)

Recombinant monoclonal antibody to E. coli Shiga-like toxin II B. Urtoxazumab is a humanized monoclonal antibody against diarrhoea caused by Escherichia coli, serotype O121. The drug is designed to bind to a toxin of this bacterium, so that it can be more easily broken down and eliminated from the body.      

  • Datasheet

Specifications
Immunogen
The details of the immunogen for this antibody are not available.
Host
Mouse
Derivation
Humanized (from mouse)
Type
IgG1 - kappa
Specificity
Tested positive against native E. coli antigen.
Species Reactivity
E. coli
Applications
Suitable for use in WB, FuncS, IF, Neut, ELISA, FC, IP and most other immunological methods.
CAS NO.
502496-16-4
Generic Name
Urtoxazumab
M.W.
144.6 kDa
Related Disease
Staphylococcal sepsis in infants with low birth weight
Target
Alternative Names
Urtoxazumab;502496-16-4;HuVTm1.1;E. coli Shiga-like toxin II B;E. coli

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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