Recombinant Anti-HBeAg Intrabody [(D-Arg)9] (CAT#: IAB-B037(A))
Recombinant anti-HBeAg intrabody linked to (D-Arg)9 works within cells and binds specifically to HBeAg, expressed in E. coli cells. The development of new therapies that target viral proteins, such as HBeAg, which regulates of the immune system, may offer a new wave of potential therapeutics to circumvent progression to CHB and liver disease.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Specifications
- Immunogen
- hepatitis B e antigen
- Host Species
- llama
- Type
- vhh-(D-Arg)9
- Cell Penetrating Peptide
- (D-Arg)9
It has been proven that polyarginine peptides composed of nine arginine amino acids (Arg-9) are able to translocate across cells very efficiently. This raises the question if molecular dynamics simulations would show a similar pathway for this highly hydrophilic and charged peptide as predicted for the Tat peptide. The simplicity of Arg-9 over other CPPs also helps isolate the role of the Arg sidechain on the translocation without the effect of other sidechains. Therefore, in this work we study computationally the translocation of Arg-9 through a lipid bilayer and show that the translocation mechanism is the same as for the Tat peptide.
- Species Reactivity
- HBV
- Applications
- Used for immunoassay techniques such as: Western blot; Immunocytochemistry; Functional studies
Product Property
- Purity
- >90% assessed by SDS-PAGE
- Storage
- 4°C or -20°C, avoid repeated freezing and thawing.
Target
- Alternative Names
- HBeAg; hepatitis B e antigen; Core antigen; Core protein antibody; HBe antigen; HBeAg; HBVgp4; Pre C,C; Precore protein; Precore/core; Precore/core ORF; Precore/core protein
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Intrabody Products
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B037(G) | Recombinant Anti-HBeAg Intrabody [+36 GFP] | ICC, Neut, FuncS | vhh-(+36GFP) |
| IAB-B037(T) | Recombinant Anti-HBeAg Intrabody [Tat] | ELISA, WB, ICC, FuncS | vhh-Tat |
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