Recombinant Anti-HBeAg Intrabody [Tat] (CAT#: IAB-B037(T))
Recombinant anti-HBeAg intrabody in fusion with HIV Tat works within cells to bind HBeAg, expressed in E. coli cells. The development of new therapies that target viral proteins, such as HBeAg, which regulates of the immune system, may offer a new wave of potential therapeutics to circumvent progression to CHB and liver disease.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Specifications
- Immunogen
- hepatitis B e antigen
- Host Species
- llama
- Type
- vhh-Tat
- Cell Penetrating Peptide
- TAT
TAT was able to deliver different proteins, such as horseradish peroxidase and RNase A across cell membrane into the cytoplasm in different cell lines in vitro. The size range of proteins with effective delivery is from 30kDa to 120-150kDa. In one study, TAT-fused proteins are rapidly internalized by lipid raft−dependent macropinocytosis using a transducible TAT−Cre recombinase reporter assay on live cells. In another study, a TAT-fused protein was delivered into mitochondria of breast cancer cells and decreased the survival of breast cancer cells, which showed capability of TAT-fusion proteins to modulate mitochondrial function and cell survival. However, very few in vivo studies have succeeded. In one study, in vivo delivery of TAT- or penetratin-crosslinked Fab fragments yielded varied organ distributions and an overall increase in organ retention, which showed tissue localization.
- Species Reactivity
- HBV
- Applications
- Can be useful in applications such as: Enzyme-linked Immunosorbent Assay; Western blot; Immunocytochemistry; Functional studies
Product Property
- Purity
- >95% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE
- Storage
- ≤6 months at 4°C; ≥6 months at -20°C.
Target
- Alternative Names
- HBeAg; hepatitis B e antigen; Core antigen; Core protein antibody; HBe antigen; HBeAg; HBVgp4; Pre C,C; Precore protein; Precore/core; Precore/core ORF; Precore/core protein
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "HBeAg"
Select a product category from the dropdown menu below to view related products.
Please select product type
Intrabody Products
ScFv Antibody Products
Fab Antibody Products
IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B037(A) | Recombinant Anti-HBeAg Intrabody [(D-Arg)9] | WB, ICC, FuncS | vhh-(D-Arg)9 |
| IAB-B037(G) | Recombinant Anti-HBeAg Intrabody [+36 GFP] | ICC, Neut, FuncS | vhh-(+36GFP) |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for IAB-B037(T). Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Application: WB, ELISA, FuncS
-2.png)
Application: IB, ELISA, FC, FuncS
Application: Neut, Inhib, FC, ELISA
Application: ELISA
-3.jpg)
For Research Use Only. Not For Clinical Use.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
