Recombinant Human Antibody (M2J1) is capable of binding to HCMV AD-2S1 epitope of gB, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-HCMV AD-2S1 epitope of gB mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-HCMV AD-2S1 epitope of gB mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. M2J1 itself is polyspecific and recognizes multiple autoantigens, although it nevertheless exhibited fine sequence specificity for AD-2S1 in that it failed to bind detectably to the homologous peptide from CCMV
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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