Human Anti-HIV-1 V3 Recombinant Antibody (clone 3074) (CAT#: PABL-570)
Recombinant Human Antibody (3074) is capable of binding to HIV-1 V3, expressed in HEK 293 cells.
Specific Inquiry
Figure 1 Neutralization curves of anti-V3 mAb 3074 against representative HIV-1 psVs tested using the U87 target cell.
Anti-V3 mAb 3074 weas tested for neutralization against HIV-1 pseudoviruses using the U87 cell line as target cells. The titration curves from eight selected psVs and the aMLV psV control are shown.
Hioe, C. E., Wrin, T., Seaman, M. S., Yu, X., Wood, B., Self, S., ... & Zolla-Pazner, S. (2010). Anti-V3 monoclonal antibodies display broad neutralizing activities against multiple HIV-1 subtypes. PloS one, 5(4), e10254.
Specifications
- Host Species
- Human
- Type
- Human IgG1,λ
- Specificity
- HIV-1
- Species Reactivity
- HIV-1
- Clone
- 3074
- Applications
- WB 1:1000-1:10000
ELISA 1:1000-1:20000
Neut Assay-dependent
FuncS Assay-dependent
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Assay-dependent
Target
- Alternative Names
- ENV; gp160; envelope glycoprotein; Envelope surface glycoprotein gp160, precursor; hypothetical protein; Envelope surface glycoprotein gp120; Envelope transmembrane domain
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "HIV-1 V3"
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IgG Antibody Products
Fab Antibody Products
ScFv Antibody Products
ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-493 | Recombinant Anti-HIV-1 V3 Antibody | ELISA, WB, IF, FuncS | IgG |
| MHH-493 | Recombinant Human Anti-HIV-1 V3 Antibody | ELISA, WB, IF, FuncS | IgG |
| PABL-569 | Human Anti-HIV-1 V3 Recombinant Antibody (PABL-569) | WB, ELISA, Neut, FuncS | Human IgG1, λ |
| PABL-571 | Human Anti-HIV-1 V3 Recombinant Antibody (clone 1006-15D) | WB, ELISA, FuncS | Human IgG1,λ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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