Recombinant Mouse anti-Human SHANK1 Monoclonal antibody (S22-21)
CAT#: MOB-2329CT
Recombinant Mouse Monoclonall antibody to Human SHANK1, expressed in Chinese Hamster Ovary cells(CHO).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32129/381_H1_4_selected.jpg
Normal Tissue
Figure 2 IHC staining of human caudate
Immunohistochemical staining of human caudate shows strong positivity in glial cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32129/71936_B_7_7_selected.jpg
Normal Tissue
Figure 3 Lymph node
Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32130/71947_A_9_8.jpg
Normal Tissue
Figure 4 Cerebral cortex
Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32130/71947_B_9_5.jpg
Normal Tissue
Figure 5 Cerebellum
Purkinje cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32130/71947_B_8_8.jpg
Normal Tissue
Figure 6 Kidney
Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32130/71947_A_9_5.jpg
Normal Tissue
Figure 7 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32130/71947_A_5_6.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (REH, THP-1, U-138 MG, U-2 OS, U-87 MG, U-937)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000161681-SHANK1
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Specifications
- Immunogen
- Fusion protein, corresponding to amino acids 469-691 (SH3/PDZ domains) of Rat SHANK1
- Host Species
- Mouse
- Species Reactivity
- Human
- Clone
- S22-21
- Applications
- Used for immunoassay techniques such as: Western Blot; Immunohistochemistry paraffin embedded sections; Immunohistochemistry (Frozen sections); Immunocytochemistry; Immunocytochemistry/Immunofluorescence
- Conjugate
- Unconjugated
Product Property
- Purity
- Protein G purified
- Format
- Liquid
- Buffer
- Preservative: 0.09% Sodium Azide. Constituents: 50% Glycerol, PBS, pH 7.4
- Storage
- Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Target
- Alternative Names
- SHANK1; SH3 and multiple ankyrin repeat domains 1; SSTRIP; SPANK-1; synamon; SH3 and multiple ankyrin repeat domains protein 1; SSTR-interacting protein; somatostatin receptor-interacting protein;
- Gene ID
- 50944
- UniProt ID
- Q9Y566
- Protein Refseq
- NP_057232
- Function
- GKAP/Homer scaffold activity; SH3 domain binding; ankyrin repeat binding; identical protein binding; ionotropic glutamate receptor binding; protein C-terminus binding; protein binding; scaffold protein binding; somatostatin receptor binding;
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "SHANK1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6556 | Anti-SHANK1 Immunohistochemistry Kit | IHC |
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