Recombinant Mouse anti-Human SHANK1 Monoclonal antibody (S22-21) (CAT#: MOB-2329CT)
Recombinant Mouse Monoclonall antibody to Human SHANK1, expressed in Chinese Hamster Ovary cells(CHO).
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32129/381_H1_4_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32129/381_H1_4_selected.jpg
Figure 2 IHC staining of human caudate
(Immunohistochemical staining of human caudate shows strong positivity in glial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32129/71936_B_7_7_selected.jpg
(Immunohistochemical staining of human caudate shows strong positivity in glial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32129/71936_B_7_7_selected.jpg
Figure 3 Lymph node
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32130/71947_A_9_8.jpg
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32130/71947_A_9_8.jpg
Figure 4 Cerebral cortex
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32130/71947_B_9_5.jpg
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32130/71947_B_9_5.jpg
Figure 5 Cerebellum
(Purkinje cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32130/71947_B_8_8.jpg
(Purkinje cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32130/71947_B_8_8.jpg
Figure 6 Kidney
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32130/71947_A_9_5.jpg
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32130/71947_A_9_5.jpg
Figure 7 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32130/71947_A_5_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32130/71947_A_5_6.jpg
Figure 8 RNA cell line category: Cell line enhanced (REH, THP-1, U-138 MG, U-2 OS, U-87 MG, U-937)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000161681-SHANK1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000161681-SHANK1
Specifications
- Immunogen
- Fusion protein, corresponding to amino acids 469-691 (SH3/PDZ domains) of Rat SHANK1
- Host Species
- Mouse
- Species Reactivity
- Human
- Clone
- S22-21
- Applications
- Used for immunoassay techniques such as: Western Blot; Immunohistochemistry paraffin embedded sections; Immunohistochemistry (Frozen sections); Immunocytochemistry; Immunocytochemistry/Immunofluorescence
- Conjugate
- Unconjugated
Product Property
- Purity
- Protein G purified
- Format
- Liquid
- Buffer
- Preservative: 0.09% Sodium Azide. Constituents: 50% Glycerol, PBS, pH 7.4
- Storage
- Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Target
- Alternative Names
- SHANK1; SH3 and multiple ankyrin repeat domains 1; SSTRIP; SPANK-1; synamon; SH3 and multiple ankyrin repeat domains protein 1; SSTR-interacting protein; somatostatin receptor-interacting protein;
- Gene ID
- 50944
- UniProt ID
- Q9Y566
- Protein Refseq
- NP_057232
- Function
- GKAP/Homer scaffold activity; SH3 domain binding; ankyrin repeat binding; identical protein binding; ionotropic glutamate receptor binding; protein C-terminus binding; protein binding; scaffold protein binding; somatostatin receptor binding;
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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For Research Use Only. Not For Clinical Use.
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