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Recombinant Mouse anti-Human SHANK1 Monoclonal antibody (S22-21) (CAT#: MOB-2329CT)

Recombinant Mouse Monoclonall antibody to Human SHANK1, expressed in Chinese Hamster Ovary cells(CHO).


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Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32129/381_H1_4_selected.jpg
Normal Tissue
Figure 2 IHC staining of human caudate
Figure 2 IHC staining of human caudate
(Immunohistochemical staining of human caudate shows strong positivity in glial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32129/71936_B_7_7_selected.jpg
Figure 3 Lymph node
Figure 3 Lymph node
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32130/71947_A_9_8.jpg
Figure 4 Cerebral cortex
Figure 4 Cerebral cortex
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32130/71947_B_9_5.jpg
Figure 5 Cerebellum
Figure 5 Cerebellum
(Purkinje cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32130/71947_B_8_8.jpg
Figure 6 Kidney
Figure 6 Kidney
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32130/71947_A_9_5.jpg
Figure 7 Testis
Figure 7 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32130/71947_A_5_6.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (REH, THP-1, U-138 MG, U-2 OS, U-87 MG, U-937)
Figure 8 RNA cell line category: Cell line enhanced (REH, THP-1, U-138 MG, U-2 OS, U-87 MG, U-937)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000161681-SHANK1

Specifications

  • Immunogen
  • Fusion protein, corresponding to amino acids 469-691 (SH3/PDZ domains) of Rat SHANK1
  • Host Species
  • Mouse
  • Species Reactivity
  • Human
  • Clone
  • S22-21
  • Applications
  • Used for immunoassay techniques such as: Western Blot; Immunohistochemistry paraffin embedded sections; Immunohistochemistry (Frozen sections); Immunocytochemistry; Immunocytochemistry/Immunofluorescence
  • Conjugate
  • Unconjugated

Product Property

  • Purity
  • Protein G purified
  • Format
  • Liquid
  • Buffer
  • Preservative: 0.09% Sodium Azide. Constituents: 50% Glycerol, PBS, pH 7.4
  • Storage
  • Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

  • Alternative Names
  • SHANK1; SH3 and multiple ankyrin repeat domains 1; SSTRIP; SPANK-1; synamon; SH3 and multiple ankyrin repeat domains protein 1; SSTR-interacting protein; somatostatin receptor-interacting protein;
  • Function
  • GKAP/Homer scaffold activity; SH3 domain binding; ankyrin repeat binding; identical protein binding; ionotropic glutamate receptor binding; protein C-terminus binding; protein binding; scaffold protein binding; somatostatin receptor binding;

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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