PDZ domain scaffold protein anti-Human β1-adrenergic receptor
CAT#: SPD-L174
The PDZ domain that bound β1-adrenergic receptor was isolated from the library using Yeast Two-hybrid techonology. PDZ domains are modular protein-interaction domains that are specialized for binding to short peptide motifs at the extreme carboxy (C) termini of other proteins, athough they can also have other modes of interaction. After affinity maturation, PDZ domain variants were identified having affinities (KD=50 nM) for β1-adrenergic receptor as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.








Specifications
- Scaffold Name
- PDZ domain
- Origin
- PSD-95 protein
- Core Structure
- β-sheet
- Target
- β1-adrenergic receptor
- Species Reactivity
- Human
- Expression Host
- E. coli
- Affinity Constant
- 50 nM
- Applications
- ELISA; IHC; Microscopy; FC; WB; FuncS
Target
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Datasheet
MSDS
COA
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