Recombinant Anti-Human ERBB2 Antibody (Fc glycosylation) (CAT#: Gly-145LC)

This product is a human monoclonal antibody with glycosylation site in the Fc region. The antibody 1E5-ETlOl with enhanced ADCC specifically binds human ErbB2 and can be potentially used in the treatment of breast cancer.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Glyco-engineering

  • Glycosylation site
  • Asn297 in Fc region
  • Glycosylation Type
  • N-glycosylation
  • Activity
  • Enhanced ADCC

Specifications

  • Target
  • ErbB2 (Human epidermal growth factor receptor 2)
  • Host Species
  • Human
  • Type
  • Human antibody
  • Specificity
  • Human
  • Antibody Isotype
  • IgG1
  • Clone
  • 1E5-ETlOl
  • Expression Host
  • CHO-K1
  • Applications
  • ELISA

Target

  • Alternative Names
  • ERBB2; erb-b2 receptor tyrosine kinase 2; NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu; receptor tyrosine-protein kinase erbB-2; herstatin; p185erbB2; proto-oncogene Neu; c-erb B2/neu protein; proto-oncogene c-ErbB-2; metastatic lymph node gene 1
  • Related Disease
  • Breast cancer

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "ERBB2"

Intrabody

CAT Product Name Application Type
IAB-B008(A) Recombinant Anti-human ERBB2 Intrabody [(D-Arg)9] IF, FC, FuncS scFv-(D-Arg)9
IAB-B008(G) Recombinant Anti-human ERBB2 Intrabody [+36 GFP] WB, ICC, FuncS scFv-(+36GFP)
IAB-B008(T) Recombinant Anti-human ERBB2 Intrabody [Tat] ICC, Neut, FuncS scFv-Tat

Chimeric Antibody

CAT Product Name Application Type
TAB-761 Anti-ERBB2 Recombinant Antibody (Margetuximab) IF, IP, Neut, FuncS, ELISA, FC, WB IgG1 - kappa
TAB-049CT Anti-Human HER2/neu Recombinant Antibody (ChA21) IHC, Inhib, WB, Activ, FC Chimeric antibody (mouse/human)
TAB-049CT-S(P) Anti-Human HER2/neu Recombinant Antibody scFv Fragment (ChA21) WB Chimeric antibody (mouse/human)
TAB-049CT-F(E) Anti-Human HER2/neu Recombinant Antibody Fab Fragment (ChA21) WB Chimeric antibody (mouse/human)

Immunotoxin

CAT Product Name Application Type
AGTO-G022E Anti-ERBB2 immunotoxin 4D5 (scFv)-PE Cytotoxicity assay, Function study
AGTO-G022D Anti-ERBB2 immunotoxin 4D5 (scFv)-DT Cytotoxicity assay, Function study
AGTO-G022G Anti-ERBB2 immunotoxin 4D5 (scFv)-Gel Cytotoxicity assay, Function study
AGTO-G022R Anti-ERBB2 immunotoxin 4D5 (scFv)-RTA Cytotoxicity assay, Function study
AGTO-G022S Anti-ERBB2 immunotoxin 4D5 (scFv)-Sap Cytotoxicity assay, Function study

Fab Glycosylation

Deglycosylated Antibody (Non-glycosylated IgGs)

CAT Product Name Application Type
Gly-177LC Recombinant Anti-Human ERBB2 Antibody (Non-glycosylated) ELISA Humanized antibody

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0195MZ Chicken Anti-ERBB2 Polyclonal IgY WB Chicken antibody
BRD-0695MZ Chicken Anti-ERBB2 Polyclonal IgY WB Chicken antibody
BRD-0779MZ Chicken Anti-ErbB2 Polyclonal IgY ICC, IF, IHC, IP Chicken antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-737CQ Mouse Anti-ERBB2 Recombinant Antibody (clone 7.16.4) Block, IP, IF, FC Mouse IgG2a

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-468CQ Afuco™ Anti-ERBB2 ADCC Recombinant Antibody (Timigutuzumab), ADCC Enhanced ELISA, IHC, FC, IP, IF, FuncS ADCC enhanced antibody
AFC-TAB-053 Afuco™ Anti-ERBB2 ADCC Recombinant Antibody (Pertuzumab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC, IP ADCC enhanced antibody
AFC-TAB-761 Afuco™ Anti-ERBB2 ADCC Recombinant Antibody (Margetuximab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody
AFC-TAB-005 Afuco™ Anti-ERBB2 ADCC Recombinant Antibody (Trastuzumab), ADCC Enhanced FC, IP, ELISA, Neut, FuncS, IF ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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