Recombinant Anti-HER2 VHH Single Domain Antibody (PNBL-067) (CAT#: PNBL-067)
Anti-Human HER2 VHH Single Domain Antibody is a recombinant protein produced in E. coli.
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SPR
Figure 1 Characterization of Gr3 and Gr6 in solution.
Binding of Gr6 to HER2/Fc analyzed by SPR.
Baral, T. N., Chao, S. Y., Li, S., Tanha, J., Arbabi-Ghahroudi, M., Zhang, J., & Wang, S. (2012). Crystal structure of a human single domain antibody dimer formed through VH-VH non-covalent interactions. PloS one, 7(1), e30149.
Figure 2 Melting temperature (Tm) measurements of Gr6 by CD spectroscopy.
Melting temperature (Tm) measurements of Gr6 by CD spectroscopy. The CD values measured at 217 nm are plotted against temperature ranging from 25uC to 91uC.
Baral, T. N., Chao, S. Y., Li, S., Tanha, J., Arbabi-Ghahroudi, M., Zhang, J., & Wang, S. (2012). Crystal structure of a human single domain antibody dimer formed through VH-VH non-covalent interactions. PloS one, 7(1), e30149.
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- Llama VHH
- Species Reactivity
- Human
- Clone
- PNBL-067
- Applications
- Surface plasmon resonance
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Applications
- Application Notes
- The antibody was validated for Surface plasmon resonance. For details, refer to Published Data.
Target
- Alternative Names
- ERBB2; erb-b2 receptor tyrosine kinase 2; NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu; receptor tyrosine-protein kinase erbB-2; herstatin; p185erbB2; proto-oncogene Neu; c-erb B2/neu protein; proto-oncogene c-ErbB-2; metastatic lymph node gene 19 protein; human epidermal growth factor receptor 2; neuro/glioblastoma derived oncogene homolog; tyrosine kinase-type cell surface receptor HER2; neuroblastoma/glioblastoma derived oncogene homolog; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog;
- UniProt ID
- P04626
Related Resources
Bladder Cancer
Non-small Cell Lung Cancer
ErbB Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B008(A) | Recombinant Anti-human ERBB2 Intrabody [(D-Arg)9] | IF, FC, FuncS | scFv-(D-Arg)9 |
| IAB-B008(G) | Recombinant Anti-human ERBB2 Intrabody [+36 GFP] | WB, ICC, FuncS | scFv-(+36GFP) |
| IAB-B008(T) | Recombinant Anti-human ERBB2 Intrabody [Tat] | ICC, Neut, FuncS | scFv-Tat |
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