A*02:01/Human WDR7 (GLIQLVEGV) MHC Tetramer (CAT#: MHC-CN1392)

• Allele
• A*02:01

• Class
• Class I

• MHC Species
• Human

• Antigen
• WDR7

• Antigen Species
• Human

• Peptide
• GLIQLVEGV

• Conjugate
• Unconjugated

• Application
• FCM, IHC

• Antigen Introduction
• This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) that may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. The encoded protein forms the beta subunit of rabconnectin-3 and binds directly with Rab3A GDP/GTP exchange protein and indirectly with Rab3A GDP/GTP activating protein; these proteins are regulators of Rab3 small G protein family members involved in control of the calcium-dependant exocytosis of neurotransmitters. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

• Alternative Names
• TRAG

• Gene ID
• 23335

• UniProt ID
• Q9Y4E6

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