A*24:02/Human Immunodeficiency virus 1 Nef protein (RYPLTFGW) MHC Pentamer
CAT#: MHC-YC168
MHC multimers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a Pentamer of peptide/MHC complex with HIV-derived peptide of RYPLTFGW sequence covering 134-141 and A*24:02 molecule. The peptide/MHC pentamer provided here is unlabeled or fluorescent labeled such as Biotin, R-PE, APC. And all of them are available in 50, 150 or 500 tests.
Specifications
- Allele
- A*24:02
- Class
- Class I
- MHC Species
- Human
- Antigen
- Human Immunodeficiency virus 1 Nef protein
- Antigen Species
- HIV
- Peptide
- RYPLTFGW
- Range
- 134-141
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- The expression of Nef early in the viral life cycle ensures T-cell activation and the establishment of a persistent state of infection, two basic attributes of HIV infection. Viral expression of Nef induces numerous changes within the infected cell including the modulation of protein cell surface expression, cytoskeletal remodeling, and signal transduction. Since the activation state of the infected cell plays an important role in the success rate of HIV-1 infection, it is important that resting T-cells be primed to respond to T-cell receptor (TCR) stimuli. HIV-1 Nef lowers the threshold for activation of CD4+ lymphocytes, but is not sufficient to cause activation in the absence of exogenous stimuli.
- Alternative Names
- HIV1gp9; p27
- Gene ID
- 156110
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See other products for "HIV Nef"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-472 | Recombinant Anti-HIV Nef Antibody | ELISA, WB, FuncS | IgG |
| MHH-472 | Recombinant Human Anti-HIV Nef Antibody | FC, Neut, Biosensors, FuncS | IgG |
| MRO-754CQ | Mouse Anti-HIV Nef Recombinant Antibody (MRO-754CQ) | ELISA, IP, IF, WB | Mouse IgG1, κ |
| VS-0625-FY777 | Mouse Anti-nef Recombinant Antibody (clone 2506W0672) | ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-472-F(E) | Recombinant Anti-HIV Nef Antibody Fab Fragment | WB, FuncS | Fab |
| MHH-472-F(E) | Recombinant Human Anti-HIV Nef Antibody Fab Fragment | WB, Dot, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-472-S(P) | Recombinant Anti-HIV Nef Antibody scFv Fragment | IP, IF, Biosensors, FuncS | scFv |
| MHH-472-S(P) | Recombinant Human Anti-HIV Nef Antibody scFv Fragment | ELISA, WB, IF, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PNBL-022 | Recombinant Anti-HIV-1 nef VHH Single Domain Antibody (PNBL-022) | Inhib, WB, FuncS | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF576 | A*02:01/HIV Nef (LTFGWCFKL) MHC Pentamer | FCM | |
| MHC-YF577 | A*03:01/HIV Nef (QVPLRPMTYK) MHC Pentamer | FCM | |
| MHC-YF578 | A*11:01/HIV Nef (AVDLSHFLK) MHC Pentamer | FCM | |
| MHC-YF579 | A*24:02/HIV Nef (RYPLTFGWCF) MHC Pentamer | FCM | |
| MHC-YF580 | A*24:02/HIV Nef (RYPLTFGWCY) MHC Pentamer | FCM |
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