A*24:02/Human Midkine (RYNAQCQETI) MHC Pentamer (CAT#: MHC-YF562)
MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed Midkine-derived peptide of RYNAQCQETI sequence covering 110-119 and A*24:02 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.
Specific Inquiry
Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57126/996_H3_2_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57126/996_H3_2_selected.jpg
Figure 2 IHC staining of human endometrium
(Immunohistochemical staining of human endometrium shows moderate cytoplasmic positivity in glandular cells and stroma.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10055/26957_B_4_3_selected.jpg
(Immunohistochemical staining of human endometrium shows moderate cytoplasmic positivity in glandular cells and stroma.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10055/26957_B_4_3_selected.jpg
Figure 3 Colon
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10055/26957_A_8_3.jpg
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10055/26957_A_8_3.jpg
Figure 4 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10055/26957_A_4_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10055/26957_A_4_6.jpg
Figure 5 Endometrium
(Cells in endometrial stroma Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10055/26957_B_4_3.jpg
(Cells in endometrial stroma Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10055/26957_B_4_3.jpg
Figure 6 RNA cell line category: Cell line enhanced (NTERA-2, REH, SH-SY5Y)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000110492-MDK
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000110492-MDK
Specifications
- Allele
- A*24:02
- Class
- Class I
- MHC Species
- Human
- Antigen
- Midkine
- Antigen Species
- Human
- Peptide
- RYNAQCQETI
- Range
- 110-119
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a member of a small family of secreted growth factors that binds heparin and responds to retinoic acid. The encoded protein promotes cell growth, migration, and angiogenesis, in particular during tumorigenesis. This gene has been targeted as a therapeutic for a variety of different disorders. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012]
- Alternative Names
- Midkine; Neurite Outgrowth-Promoting Factor 2; Neurite Growth-Promoting Factor 2; Amphiregulin-Associated Protein; Midgestation And Kidney Protein; NEGF2;
- Gene ID
- 4192
- UniProt ID
- P21741
Downloads
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0812CL | Human Anti-MDK Recombinant Antibody (TAB-0812CL) | ELISA | Humanized antibody |
| TAB-0812CL-S(P) | Human Anti-MDK Recombinant Antibody; scFv Fragment (TAB-0812CL-S(P)) | ELISA | Humanized scFv |
| TAB-0812CL-F(E) | Human Anti-MDK Recombinant Antibody; Fab Fragment (TAB-0812CL-F(E)) | ELISA | Humanized Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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