Mouse Anti-BANP Recombinant Antibody (VS3-FY2629) (CAT#: VS3-FY2629)

• Host Species
• Mouse

• Type
• Mouse IgG

• Specificity
• BTG3 associated nuclear protein of human, mouse and rat origins

• Species Reactivity
• Human, Mouse, Rat

• Applications
• WB, IHC

• Conjugate
• Unconjugated, FITC

• MW
• The molecular weight of the target protein is approximately 56.5 kDa.

• Related Disease
• Keratoconus

• Clonality
• Monoclonal Antibody

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Western Blot: 1/500-1/1000
  Immunohistochemistry: 1/50-1/200

• Alternative Names
• BTG3 Associated Nuclear Protein; Scaffold/Matrix-Associated Region-1-Binding Protein; BEN Domain-Containing Protein 1; BEND1; SMAR1; Btg3-Associated Nuclear Protein; BEN Domain Containing 1; Protein BANP; SMARBP1

• Gene ID
• 54971

• UniProt ID
• Q8N9N5

• Sequence Similarities
• Belongs to the BANP/SMAR1 family.

• Cellular Localization
• Nucleus

• Post Translation Modifications
• Modification sites at PhosphoSitePlus
  Modification sites at neXtProt
  Glycosylation from GlyGen 1 site, 1 O-linked glycan (1 site)

• Protein Refseq
• NP_001167010.1; NP_001167011.1; NP_001167012.1; NP_001167013.1; NP_001167014.1

• Function
• Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function.
  Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer.
  Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels.
  Promotes TP53 activation, which causes cell cycle arrest (By similarity).

Secondary Antibody

• 2ND-040CQ
• Goat Anti-Mouse IgG (H&L) Antibody

Isotype Control

• MRO-A1591-YJ
• Mouse IgG Isotype control, Polyclonal

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