The crystal structure of a 1:1 complex between the German cockroach allergen Bla g 2 and the Fab′ fragment of a monoclonal antibody 7C11 was solved at 2.8-Å resolution. Bla g 2 binds to the antibody through four loops that include residues 60-70, 83-86, 98-100, and 129-132. The epitope for mAb 7C11 is important surface determinants overlapping with IgE antibody binding sites and inhibit IgE antibody binding.
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• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-112 | Recombinant Anti-Bla g 2 Antibody | WB, FC, FuncS | IgG |
MHH-112 | Recombinant Human Anti-Bla g 2 Antibody | RIA, WB, FuncS | IgG |
PABC-013 | Recombinant Mouse Anti-B. germanica Bla g 2 Antibody (7C11) | ELISA | IgG |
HPAB-S0180-YC | Mouse Anti-Bla g 2 Recombinant Antibody (clone 7C11) | ELISA | Mouse IgG |
VS-0322-LC62 | Rabbit Anti-Bla g 2 Recombinant Antibody (clone 4C3) | ELISA |
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