Human Anti-COL4A3 Recombinant Antibody (clone 2D6); Fab Fragment
CAT#: FAMAB-0340JF-F(E)
Recombinant monoclonal antibody specially binds to the noncollagenous‐1 domain of type IV collagen. This human anti-type IV collagen antibody (2D6) can be potentially used in the treatment of patients with anti‐glomerular basement membrane nephritis or Goodpasture syndrome.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HeLa
Immunofluorescent staining of human cell line HeLa shows localization to endoplasmic reticulum & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42064/1054_B7_2_selected.jpg
Normal Tissue
Figure 2 IHC staining of human stomach
Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42064/ihc_selected.jpg
Normal Tissue
Figure 3 Colon
Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42064/90201_A_8_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42064/90201_A_9_5.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42064/90201_A_4_6.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (HeLa, hTERT-RPE1, Karpas-707, RPTEC TERT1, U-266/70)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000169031-COL4A3
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Specifications
- Immunogen
- Bovine alpha3(IV)NC1 collagen
- Host Species
- Human
- Type
- Human Fab
- Specificity
- Bovine COL4A3
- Species Reactivity
- Bovine
- Clone
- 2D6
- Applications
- ELISA, FuncS
- Related Disease
- Anti‐glomerular basement membrane nephritis, Goodpasture syndrome
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Collagen type IV alpha 3 chain; COL4A3
- Gene ID
- 317711
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone 2D6"
- CAT
- Product Name
See other products for "COL4A3"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1503z | Mouse Anti-COL4A3 Recombinant Antibody (clone 34D3) | ELISA, IF, IHC | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0340JF | Human Anti-COL4A3 Recombinant Antibody (clone 2D6) | ELISA, FuncS | Human IgM, λ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0340JF-S(P) | Human Anti-COL4A3 Recombinant Antibody (clone 2D6); scFv Fragment | ELISA, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1593 | Anti-COL4A3 Immunohistochemistry Kit | IHC |
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