Human Anti-COL4A3 Recombinant Antibody (clone 2D6) (CAT#: FAMAB-0340JF)
Recombinant monoclonal antibody specially binds to the noncollagenous‐1 domain of type IV collagen. This human anti-type IV collagen antibody (2D6) can be potentially used in the treatment of patients with anti‐glomerular basement membrane nephritis or Goodpasture syndrome.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HeLa
(Immunofluorescent staining of human cell line HeLa shows localization to endoplasmic reticulum & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/42064/1054_B7_2_selected.jpg
(Immunofluorescent staining of human cell line HeLa shows localization to endoplasmic reticulum & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/42064/1054_B7_2_selected.jpg
Figure 2 IHC staining of human stomach
(Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/42064/ihc_selected.jpg
(Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/42064/ihc_selected.jpg
Figure 3 Colon
(Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/42064/90201_A_8_3.jpg
(Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/42064/90201_A_8_3.jpg
Figure 4 Kidney
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/42064/90201_A_9_5.jpg
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/42064/90201_A_9_5.jpg
Figure 5 Testis
(Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/42064/90201_A_4_6.jpg
(Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/42064/90201_A_4_6.jpg
Figure 6 RNA cell line category: Cell line enhanced (HeLa, hTERT-RPE1, Karpas-707, RPTEC TERT1, U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000169031-COL4A3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000169031-COL4A3
Specifications
- Immunogen
- Bovine alpha3(IV)NC1 collagen
- Host Species
- Human
- Type
- Human IgM, λ
- Specificity
- Bovine COL4A3
- Species Reactivity
- Bovine
- Clone
- 2D6
- Applications
- ELISA, FuncS
- Related Disease
- Anti‐glomerular basement membrane nephritis, Goodpasture syndrome
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Collagen type IV alpha 3 chain; COL4A3
- Gene ID
- 317711
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibodies
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IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1503z | Mouse Anti-COL4A3 Recombinant Antibody (clone 34D3) | ELISA, IF, IHC | Mouse IgM |
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For Research Use Only. Not For Clinical Use.
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