Mouse Anti-DNA-RNA hybrid Recombinant Antibody (clone S9.6) (CAT#: FAMAB-1865CQ)
This product is a recombinant mouse antibody that recognizes DNA-RNA hybrid. The antibody was purified by affinity chromatography. It can be used in ChIP, DB, EMSA, FISH, ICC, IP, IF.
Specific Inquiry
SPR
Figure 1 Effect of DNA-RNA hybrid length on S9.6 scFv affinity as determined by SPR in 1x HBS-T buffer.
DNA-RNA hybrids of six different lengths were tested via SPR to determine the minimum size of the epitope that S9.6 would bind. The S9.6 scFv displayed similar affinities to hybrids having 8, 10, 15 and 23 base pairs, with affinities averaging 0.5 nM.
Phillips, D. D., Garboczi, D. N., Singh, K., Hu, Z., Leppla, S. H., & Leysath, C. E. (2013). The sub‐nanomolar binding of DNA–RNA hybrids by the single‐chain Fv fragment of antibody S9. 6. Journal of Molecular Recognition, 26(8), 376-381.
Specifications
- Immunogen
- Synthetic DNA/RNA antigen
- Host Species
- Mouse
- Type
- Mouse IgG
- Clone
- S9.6
- Applications
- ChIP, DB, EMSA, FISH, ICC, IP, IF
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- DNA-RNA hybrids
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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