AbPlus™ Anti-GM2A Magnetic Beads (VS-0724-YC746) (CAT#: VS-0724-YC746)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-GM2A specific antibody

• Target
• GM2A

• Immunogen
• Recombinant human GM2A, aa 1-193.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]

• Alternative Names
• GM2 Ganglioside Activator; Cerebroside Sulfate Activator Protein; Sphingolipid Activator Protein 3; GM2-AP; SAP-3; GM2 Ganglioside Activator Protein; Shingolipid Activator Protein 3; Ganglioside GM2 Activator;

• Gene ID
• 2760

• UniProt ID
• P17900

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