Human Anti-GPRV Recombinant Antibody (clone III-20) (CAT#: FAMAB-0164WJ)

This product is a human monoclonal antibody against the glycoprotein antigen of the rabies virus from a human synthetic scFv phage display library and their fusion with the Fc region of human IgG1. This antibody can be used in applications, such as ELISA, WB, Neut.

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  • Published Data
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  • COA
WB

Figure 1 Western blot analysis showing the position of the scFv-Fc fusion protein.

Figure 1 Western blot analysis showing the position of the scFv-Fc fusion protein.

Lane 1, Molecular weight markers (97.4 kD-21.5 kD); Lane 2, III-20-Fc; Lane 3, IV-67-Fc.

Ray, K., Embleton, M. J., Jailkhani, B. L., Bhan, M. K., & Kumar, R. (2001). Selection of single chain variable fragments (scFv) against the glycoprotein antigen of the rabies virus from a human synthetic scFv phage display library and their fusion with the Fc region of human IgG1. Clinical and experimental immunology, 125(1), 94–101.

DB

Figure 2 Dot blot analysis showing the specific binding of fusion proteins to GPRV and PV11.

Figure 2 Dot blot analysis showing the specific binding of fusion proteins to GPRV and PV11.

These were detected with III-20-Fc (lane 1), IV-67-Fc (lane 2), Fc (lane 3, negative control) and HRIG (lane 4, positive control) followed by HRP conjugated anti-human IgG.

Ray, K., Embleton, M. J., Jailkhani, B. L., Bhan, M. K., & Kumar, R. (2001). Selection of single chain variable fragments (scFv) against the glycoprotein antigen of the rabies virus from a human synthetic scFv phage display library and their fusion with the Fc region of human IgG1. Clinical and experimental immunology, 125(1), 94–101.

IF

Figure 3 Membrane immunofluorescence of PV11 infected Vero cells with (a) III-20-Fc, (b) IV-67-Fc and (c) HRIG.

Figure 3 Membrane immunofluorescence of PV11 infected Vero cells with (a) III-20-Fc, (b) IV-67-Fc and (c) HRIG.

Magnifications indicated are on the film. Live single cell suspensions of PV11 infected Vero cells were treated with either the fusion proteins, or HRIG as primary antibodies followed by FITC conjugated anti-human IgG.

Ray, K., Embleton, M. J., Jailkhani, B. L., Bhan, M. K., & Kumar, R. (2001). Selection of single chain variable fragments (scFv) against the glycoprotein antigen of the rabies virus from a human synthetic scFv phage display library and their fusion with the Fc region of human IgG1. Clinical and experimental immunology, 125(1), 94–101.


Specifications

  • Host Species
  • Human
  • Derivation
  • Phage Display Library
  • Type
  • Human IgG1
  • Species Reactivity
  • GPRV
  • Clone
  • III-20
  • Applications
  • ELISA, WB, Neut
  • Related Disease
  • GPRV infection

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Rabies lyssavirus; GPRV

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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