Recombinant Mouse Anti-HAdV-5 L3 Antibody (9C12) (CAT#: PABC-469)
This product is a recombinant Mouse antibody that can recognize HAdV-5 L3. The anti-Adv5 antibody 9C12 targets hexon, the primary capsid component, which assembles into 240 trimers to form the faces of each icosahedral virion.
Specific Inquiry
BL
Figure 1 9C12 binding blocks accumulation of HAdV-5 at the nuclear envelope.
9C12 binding blocks accumulation of HAdV-5 at the nuclear envelope. Representative A549 cells at the indicated times postinfection with Ad5.eGFP in the presence or absence of the neutralizing 9C12 antibody stained for tubulin (FITC, green), Ad5.eGFP (Cy3, red), and the nucleus (DAPI, blue) are depicted as z-profiles of sequential deconvolved z-series. Percentages are the colocalization values for each cell.
Smith, J. G., Cassany, A., Gerace, L., Ralston, R., & Nemerow, G. R. (2008). Neutralizing antibody blocks adenovirus infection by arresting microtubule-dependent cytoplasmic transport. Journal of virology, 82(13), 6492-6500.
Specifications
- Immunogen
- Purified human adenovirus serotype 5
- Host Species
- Mouse
- Type
- Mouse IgG1, κ
- Specificity
- HAdV-5 L3
- Species Reactivity
- HAdV-5
- Clone
- 9C12
- Applications
- ELISA, FC, BL, IF, IP, WB
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Western Blot, Blocking, Enzyme-linked Immunosorbent Assay, Immunofluorescence, Immunoprecipitation and Flow Cytometry. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- HAdV-5 L3; Human adenovirus C serotype 5 Hexon protein
- UniProt ID
- P04133
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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ScFv Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-468 | Recombinant Human Anti-HAdV-5 L3 Antibody (hu9C12) | ELISA, FC, BL, IF, IP, WB | Human IgG1, κ |
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To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# PABC-469, RRID: AB_3111592)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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