Human Anti-HIV-1 gp120 Recombinant Antibody (clone 1331E) (CAT#: MRO-3295CQ)

Recombinant human antibody to gp120. This antibody inhibits sCD4 binding to rec gp120 LAI.


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Cyt

Figure 1 ADCP activity of immune sera from animals that received with gp120A244 or gp120A244/mAb complexes.

Figure 1 ADCP activity of immune sera from animals that received with gp120A244 or gp120A244/mAb complexes.

Pooled sera from groups of mice immunized with gp120 AE.A244 in complex with different mAbs or no mAb were tested for the ability to mediate ADCP using phagocytic THP-1 cells and fluorescent beads coated with gp120.

Hioe, C. E., Kumar, R., Upadhyay, C., Jan, M., Fox, A., Itri, V., ... & Tuen, M. (2018). Modulation of antibody responses to the V1V2 and V3 regions of HIV-1 envelope by immune complex vaccines. Frontiers in immunology, 9, 2441.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG1, κ
  • Specificity
  • Recognizes HIV-1 gp120
  • Species Reactivity
  • HIV-1
  • Clone
  • 1331E
  • Applications
  • Cyt, Inhib

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been reported for use in Cytotoxicity Assay.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP120; gp120; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "Clone 1331E"

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Recombinant Antibody

Chimeric Antibody

CAT Product Name Application Type
MRO-135LC Anti-HIV-1 gp120 Recombinant Antibody (CAG1-51-4) ELISA, WB, Neut Chimeric antibody (mouse/human)
MRO-135LC-S(P) Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (CAG1-51-4) ELISA, WB Chimeric antibody (mouse/human)
MRO-135LC-F(E) Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (CAG1-51-4) ELISA, WB Chimeric antibody (mouse/human)

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-4220 Rabbit Anti-HIV-1 gp120 Recombinant Antibody (clone SI299DS) WB, ELISA Rabbit IgG

Humanized Antibody

CAT Product Name Application Type
PABX-101-S(P) Human Anti-HIV-1 gp120 Recombinant Antibody (clone PG9); scFv Fragment WB, ELISA, FuncS Human scFv

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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