Human Anti-HIV-1 gp120 Recombinant Antibody (clone BM12) (CAT#: MRO-3089CQ)
Recombinant human antibody to gp120. BM12 has broad cross-clade neutralization of primary isolates.
Specific Inquiry
FC
Figure 1 Islets were isolated from two male bm12 donors, divided into two equal aliquots (∼200 islets each) and analyzed for passenger TCRβ+ cells and CD19+ B cells by flow cytometry.
Shown is a dot plot for one aliquot along with quadrant percentages.
Chan, W. F., Razavy, H., & Anderson, C. C. (2008). Differential susceptibility of allogeneic targets to indirect CD4 immunity generates split tolerance. The Journal of Immunology, 181(7), 4603-4612.
FuncS
Figure 2 Marilyn cells failed to proliferate when stimulated by male bm12 cells.
Female Marilyn spleen cells were stimulated with titrated numbers of male B6 (positive control) or female B6 (negative control), or male bm12 spleen cells in vitro. Data for male bm12 stimulation represent mean and SEM of five animals.
Chan, W. F., Razavy, H., & Anderson, C. C. (2008). Differential susceptibility of allogeneic targets to indirect CD4 immunity generates split tolerance. The Journal of Immunology, 181(7), 4603-4612.
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Recognizes HIV-1 gp120
- Species Reactivity
- HIV-1
- Clone
- BM12
- Applications
- FC, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Flow Cytometry and Function Assay.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP120; gp120; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone BM12"
See other products for "HIV-1 gp120"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-135 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone PGT135) | ELISA, Neut | Human IgG |
| PABL-142 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 412d) | Neut, WB, ELISA, FuncS | Human IgG |
| PABL-155 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone VRC03) | WB, ELISA, Neut, FuncS | Human IgG |
| PABL-156 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone VRC-CH31) | WB, ELISA, Neut, FuncS | Human IgG |
| PABL-160 | Mouse Anti-HIV-1 gp120 Recombinant Antibody (clone 59.1) | WB, ELISA, FuncS | Mouse IgG1, κ |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBZ-164 | Human Anti-HIV-1 gp120 Recombinant Antibody; Fab Fragment (PFBZ-164) | Neut | Human Fab |
| PFBZ-165 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone GL-VRC01); Fab Fragment | Neut | Human Fab |
| MRO-3568CQ-S(P) | Mouse Anti-HIV-1 gp120 Recombinant Antibody (clone D24); scFv Fragment | ELISA, Block | Mouse scFv |
| MRO-3569CQ-S(P) | Mouse Anti-HIV-1 gp120 Recombinant Antibody (clone D25); scFv Fragment | ELISA, Block | Mouse scFv |
| MRO-3570CQ-S(P) | Mouse Anti-HIV-1 gp120 Recombinant Antibody (clone D27); scFv Fragment | ELISA, Block | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBZ-164 | Human Anti-HIV-1 gp120 Recombinant Antibody; scFv Fragment (PSBZ-164) | Neut | Human scFv |
| PSBZ-165 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone GL-VRC01); scFv Fragment | Neut | Human scFv |
| PSBW-160 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone F105); scFv Fragment | FC, Neut | Human scFv |
| PSBW-178 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone b12); scFv Fragment | Neut, ELISA | Human scFv |
| FAMAB-0177CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone BAT123); Fab Fragment | Neut | Chimeric (mouse/human) Fab |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-028LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-028LC-VHH) | ELISA | Single domain antibody |
| MRO-029LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-029LC-VHH) | ELISA | Single domain antibody |
| MRO-030LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-030LC-VHH) | ELISA | Single domain antibody |
| MRO-031LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-031LC-VHH) | ELISA | Single domain antibody |
| MRO-032LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-032LC-VHH) | ELISA | Single domain antibody |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-053LC | Anti-HIV-1 gp120 Recombinant Antibody (W1-10) | ELISA | Mouse antibody |
| MRO-054LC | Anti-HIV-1 gp120 Recombinant Antibody (W1-21) | ELISA | Mouse antibody |
| MRO-055LC | Anti-HIV-1 gp120 Recombinant Antibody (W1-43) | ELISA | Mouse antibody |
| MRO-056LC | Anti-HIV-1 gp120 Recombinant Antibody (W1-45) | ELISA | Mouse antibody |
| MRO-057LC | Anti-HIV-1 gp120 Recombinant Antibody (W1-63) | ELISA | Mouse antibody |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-135LC | Anti-HIV-1 gp120 Recombinant Antibody (CAG1-51-4) | ELISA, WB, Neut | Chimeric antibody (mouse/human) |
| MRO-135LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (CAG1-51-4) | ELISA, WB | Chimeric antibody (mouse/human) |
| MRO-135LC-F(E) | Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (CAG1-51-4) | ELISA, WB | Chimeric antibody (mouse/human) |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-155LC | Anti-HIV-1 gp120 Recombinant Antibody (GP44) | ELISA | Human antibody |
| MRO-156LC | Anti-HIV-1 gp120 Recombinant Antibody (GP68) | ELISA, Inhib | Human antibody |
| MRO-157LC | Anti-HIV-1 gp120 Recombinant Antibody (MN215) | ELISA | Human antibody |
| MRO-161LC | Human Anti-HIV-1 gp120 Recombinant Antibody (MRO-161LC) | ELISA | Human IgG1, κ |
| MRO-162LC | Human Anti-HIV-1 gp120 Recombinant Antibody (MRO-162LC) | ELISA, FC, Neut, SPR | Human IgG1, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4220 | Rabbit Anti-HIV-1 gp120 Recombinant Antibody (clone SI299DS) | WB, ELISA | Rabbit IgG |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-101-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone PG9); scFv Fragment | WB, ELISA, FuncS | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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