Human Anti-HIV-1 gp160 Recombinant Antibody (clone 697-D (697D, 697-30D)) (CAT#: MRO-3778CQ)
This product is a recombinant human anti-HIV-1 monoclonal antibody. 697-D (697D, 697-30D) specifically binds to gp160(161-180).
Specific Inquiry
Inhib
Figure 1 Quantification of antibody inhibition of HIV-1 Env fusion using the SRFA.
HIV-1HXB2 Env fusion inhibition properties of anti-gp120 monoclonal antibodies 17b, 2G12, 48d, 697-30D or VRC03 at 10 μg/mL or one μg/mL of eCD4-Ig.
Yang, E., Gardner, M. R., Zhou, A. S., Farzan, M., Arvin, A. M., & Oliver, S. L. (2018). HIV-1 inhibitory properties of eCD4-Igmim2 determined using an Env-mediated membrane fusion assay. PloS one, 13(10).
Neut
Figure 2 HIV neutralizing serum inhibition of HIV-1SF2 Env fusion.
Co-cultures of CHO-DSP1 cells transiently expressing HIV-1SF2 Env and Hela.
Yang, E., Gardner, M. R., Zhou, A. S., Farzan, M., Arvin, A. M., & Oliver, S. L. (2018). HIV-1 inhibitory properties of eCD4-Igmim2 determined using an Env-mediated membrane fusion assay. PloS one, 13(10).
ELISA
Figure 3 ELISA experiments to map the specificity of MAb 697-D.
Inhibition of binding of human MAb 697-D by murine MAbs BAT-085, SC-258, and G3-4.
Gorny, M. K., Moore, J. P., Conley, A. J., Karwowska, S., Sodroski, J., Williams, C., ... & Zolla-Pazner, S. (1994). Human anti-V2 monoclonal antibody that neutralizes primary but not laboratory isolates of human immunodeficiency virus type 1. Journal of virology, 68(12), 8312-8320.
Specifications
- Host Species
- Human
- Type
- Human IgG1, λ
- Specificity
- Recognizes HIV-1 gp160(161-180)
- Species Reactivity
- HIV-1
- Clone
- 697-D (697D, 697-30D)
- Applications
- Neut, Inhib, ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HIV-1 gp160 antibody has been reported in applications of Neutralization, Inhibition, Enzyme-linked Immunosorbent Assay.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP160; gp160; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-177 | Human Anti-HIV-1 gp160 Recombinant Antibody; scFv Fragment (PSBL-177) | WB, ELISA, Neut, FuncS | Human scFv |
| PSBL-178 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 3H+109L); scFv Fragment | WB, ELISA, FuncS | Human scFv |
| PSBL-179 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone PGT128); scFv Fragment | WB, ELISA, FuncS | Human scFv |
| PSBL-180 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC08C); scFv Fragment | WB, ELISA, Neut, FuncS | Human scFv |
| PFBW-163 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 268-D); Fab Fragment | ELISA, Neut | Human Fab |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABW-163 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 268-D) | ELISA, Neut | Human IgG1,λ |
| MRO-3673CQ | Chimpanzee Anti-HIV-1 gp160 Recombinant Antibody (clone C311E) | FC, FuncS | Chimpanzee IgG1 |
| MRO-3674CQ | Human Anti-HIV-1 gp160 Recombinant Antibody (clone HGN35) | ELISA | Human IgG |
| MRO-3675CQ | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 10-188) | Neut, WB, ELISA | Human IgG |
| MRO-3676CQ | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 10-380) | Neut | Human IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-180 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 2558); scFv Fragment | ELISA, Neut | Human scFv |
| MRO-3768CQ-F(E) | Human Anti-HIV-1 gp160 Recombinant Antibody (clone m66.6 Y100cHCS); Fab Fragment | ELISA, Neut | Human Fab |
| MRO-3769CQ-F(E) | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 1131-A); Fab Fragment | ELISA, WB | Human Fab |
| MRO-3771CQ-F(E) | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 1A1); Fab Fragment | ELISA, WB | Human Fab |
| MRO-3772CQ-F(E) | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 4D4); Fab Fragment | ELISA, WB | Human Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-075LC | Anti-HIV-1 gp160 Recombinant Antibody (24G3) | WB, ELISA | Human antibody |
| MRO-080LC | Anti-HIV-1 gp160 Recombinant Antibody (81C7) | ELISA | Human antibody |
| MRO-091LC | Anti-HIV-1 gp160 Recombinant Antibody (MAb CL1) | ELISA | Human antibody |
| MRO-100LC-S(P) | Anti-HIV-1 gp160 Recombinant Antibody scFv Fragment (N7019b) | ELISA | Human antibody |
| MRO-101LC-S(P) | Anti-HIV-1 gp160 Recombinant Antibody scFv Fragment (K24-3b) | ELISA | Human antibody |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-086LC | Anti-HIV-1 gp160 Recombinant Antibody (1C1) | ELISA | Mouse antibody |
| MRO-087LC | Anti-HIV-1 gp160 Recombinant Antibody (1H9) | ELISA | Mouse antibody |
| MRO-089LC | Anti-HIV-1 gp160 Recombinant Antibody (2H8) | ELISA | Mouse antibody |
| MRO-086LC-S(P) | Anti-HIV-1 gp160 Recombinant Antibody scFv Fragment (1C1) | ELISA | Mouse antibody |
| MRO-087LC-S(P) | Anti-HIV-1 gp160 Recombinant Antibody scFv Fragment (1H9) | ELISA | Mouse antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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