Human Anti-HIV-1 Tat Recombinant Antibody (clone G2) (CAT#: MRO-4312CQ)
Recombinant human antibody to Tat. G2 binds strongly to soluble rTAT protein and to denatured rTAT, suggesting that the epitope is linear. G2 recognized HIV-1 clade B Tat proteins Bru and HXB2, but did not bind to clade E (CM240), clade C (92Br), clade D.
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FC
Figure 2 Effect of PI3K pharmacological inhibitors on the antiapoptotic effect of Tat.
The percentage of apoptotic KS cells subjected to the TUNEL assay after 24 h of
incubation with different stimuli.
Deregibus, M. C., Cantaluppi, V., Doublier, S., Brizzi, M. F., Deambrosis, I., Albini, A., & Camussi, G. (2002). HIV-1-Tat protein activates phosphatidylinositol 3-kinase/AKT-dependent survival pathways in Kaposi's sarcoma cells. Journal of Biological Chemistry, 277(28), 25195-25202.
Specifications
- Host Species
- Human
- Type
- Human IgG1, κ
- Specificity
- Recognizes HIV-1 Tat
- Species Reactivity
- HIV-1
- Clone
- G2
- Applications
- WB, FC
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HIV-1 Tat antibody has been reported in applications of Western Blot, Flow Cytometry.
Target
- Alternative Names
- TAT; p14; Tat; Transactivating regulatory protein; HIV-1
- Gene ID
- 155871
- UniProt ID
- P04608
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1025CQ | Mouse Anti-HIV-1 Tat Recombinant Antibody (clone 02-010) | WB, IP | Mouse IgM |
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