Human Anti-HIV CD4bs Recombinant Antibody (clone N49P11) (CAT#: FAMAB-0179WJ)

This product is a human antibody targets HIV CD4bs. This antibody can be used in applications, such as ELISA, WB, Neut.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Datasheet
  • MSDS
  • COA
SPR

Figure 1 Surface Plasmon Resonance Analysis of N49 P Series mAbs to HIV-1 Envelope Antigens.

Figure 1 Surface Plasmon Resonance Analysis of N49 P Series mAbs to HIV-1 Envelope Antigens.

The binding kinetics for BaL-gp120 or D368R with mAb captured on Protein A-coated chips are shown. Datasets with significant dose response were globally fit to a 1:1 binding model to obtain the kinetic parameters of the binding. All mAbs tested bound strongly to gp120 monomer but exhibited weak binding to D368R.

Sajadi, M. M., Dashti, A., Rikhtegaran Tehrani, Z., Tolbert, W. D., Seaman, M. S., Ouyang, X., Gohain, N., Pazgier, M., Kim, D., Cavet, G., Yared, J., Redfield, R. R., Lewis, G. K., & DeVico, A. L. (2018). Identification of Near-Pan-neutralizing Antibodies against HIV-1 by Deconvolution of Plasma Humoral Responses. Cell, 173(7), 1783–1795.e14.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG
  • Specificity
  • HIV CD4bs
  • Species Reactivity
  • HIV
  • Clone
  • N49P11
  • Applications
  • ELISA, WB, Neut
  • Related Disease
  • HIV infection

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Human immunodeficiency virus; HIV

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone N49P11"

See other products for "HIV CD4bs"

Customer Reviews and Q&As

Submit a review or a question
There are currently no Customer reviews or questions for FAMAB-0179WJ. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.

For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

© 2024 Creative Biolabs.
  • 0
  • 0
Cart

    Go to compare