Mouse Anti-KT Recombinant Antibody (clone H6) (CAT#: VS-0623-WK31)
The antibody clone H6 was produced by immunizing mouse with Killer toxin (KT) produced by the yeast Pichia anomala. It can be used for detection of Yeast KT in DB and IF staining.
Specific Inquiry
FuncS
Figure 1 Kaplan-Meier survival curve of normal BALB/c with infection challenge treated with 50 μg KP, SP, or fluconazole, or untreated.
BALB/c (eight per group) were infected intravenously on day 0 with 107 C. albicans cells (strain SA-40; predetermined to correspond to five LD50's) and then intraperitoneally injected with 50 μg of KP (VS-0623-WK31), SP, or fluconazole in saline at 1, 24, and 48 h, after the infectious challenge.
FuncS
Figure 2 Candidacidal activity of KP (VS-0623-WK31) in vivo.
All rats (five per group) were challenged intravaginally with 107 C. albicans cells (strain SA-40) in 0.1 ml of physiological saline on day 0 and then sampled for initial intravaginal CFU. The therapeutics (KP (VS-0623-WK31), SP, and fluconazole; 50 μg each) were administered 1, 24, and 48 h after the challenge.
Specifications
- Immunogen
- Killer toxin (KT) produced by the yeast Pichia anomala
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Yeast KT
- Species Reactivity
- Yeast
- Clone
- H6
- Applications
- DB, IF, FuncS
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No Preservative
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- In vivo therapeutic activity: 50 or 100 μg in phosphate-buffered saline (0.1 mL)
In vitro killer activity: 100 μg/mL
Target
- Alternative Names
- RELB Proto-Oncogene; NF-KB Subunit; V-Rel Avian Reticuloendotheliosis Viral Oncogene Homolog B (Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 3); I-REL; V-Rel Reticuloendotheliosis Viral Oncogene Homolog B; Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 3; Transcription Factor RelB; IMD53; REL-B; IREL
- Long Name
- Killer toxin
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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