Rabbit Anti-LMNB2 Recombinant Antibody (VS3-FY2790) (CAT#: VS3-FY2790)
The anti-LMNB2 antibody is a rabbit recombinant monoclonal antibody. It has been specifically designed to target the human LMNB2 protein. It cross-reacts with mouse, rat species. This monoclonal antibody proves valuable in disease research related to Epilepsy, Progressive Myoclonic, 9 and Lipodystrophy, Partial, Acquired.
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Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nuclear membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62477/1227_H10_3_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to nuclear membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62477/1227_H10_3_selected.jpg
Figure 2 IHC staining of human cerebral cortex
(Immunohistochemical staining of human cerebral cortex shows strong positivity in nuclei and nuclear membranes of neurons.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22593/ihc_selected.jpg
(Immunohistochemical staining of human cerebral cortex shows strong positivity in nuclei and nuclear membranes of neurons.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22593/ihc_selected.jpg
Figure 3 IHC staining of human bone marrow
(High expression. RNA expression: 17.3 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62477/143764_B_4_4_val_selected.jpg
(High expression. RNA expression: 17.3 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62477/143764_B_4_4_val_selected.jpg
Figure 4 IHC staining of human parathyroid gland
(Low expression. RNA expression: 3.6 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62477/143764_A_3_8_val_selected.jpg
(Low expression. RNA expression: 3.6 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62477/143764_A_3_8_val_selected.jpg
Figure 5 Colon
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62477/143764_A_9_3.jpg
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62477/143764_A_9_3.jpg
Figure 6 Liver
(Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62477/143764_A_9_4.jpg
(Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62477/143764_A_9_4.jpg
Figure 7 Kidney
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62477/143764_A_9_5.jpg
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62477/143764_A_9_5.jpg
Figure 8 Testis
(Cells in seminiferous ducts
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62477/143764_A_6_6.jpg
(Cells in seminiferous ducts
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62477/143764_A_6_6.jpg
Figure 9 epididymis
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47863/134959_A_3_6.jpg
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47863/134959_A_3_6.jpg
Figure 10 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous nuclear
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62477/143764_A_8_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous nuclear
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62477/143764_A_8_8.jpg
Figure 11 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000176619-LMNB2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000176619-LMNB2
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat LMNB2
- Species Reactivity
- Human, Mouse, Rat
- Applications
- Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation
- Conjugate
- Unconjugated, FITC
- Related Disease
- Epilepsy, Progressive Myoclonic, 9 and Lipodystrophy, Partial, Acquired
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Immunoprecipitation: 1/20
Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/100
Immunocytochemistry: 1/50-1/200
Target
- Alternative Names
- LMNB2; Lamin B2; Epididymis Secretory Sperm Binding Protein; Lamin B3; MCPH27; LAMB2; EPM9
- Gene ID
- 84823
- UniProt ID
- Q03252
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2385CT | Recombinant Mouse anti-Human LMNB2 Monoclonal antibody (C5G9) | ICC, FC, IHC-Fr, WB, IP | |
| MRO-2012-CN | Rabbit Anti-LMNB2 Polyclonal Antibody (MRO-2012-CN) | WB | Rabbit IgG |
| MRO-2013-CN | Rabbit Anti-LMNB2 Polyclonal Antibody (MRO-2013-CN) | WB, IF, IHC | Rabbit IgG |
| ZG-1045F | Mouse Anti-LMNB2 Recombinant Antibody (clone LN43) | FC, IHC-Fr, WB | Mouse IgG1 |
| VS7-0425-WR304 | Mouse Anti-LMNB2 Recombinant Antibody (clone 2E2F4) | WB, IHC, ICC, FC | Mouse IgG2b |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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