Rabbit Anti-Oprk1 Recombinant Antibody (clone R03-2A5) (CAT#: VS3-FY1753)
kappa opioid receptor antibody detected positive in western blot analysis of kappa opioid receptor in rat brain lysates. The recombinant monoclonal antibody specifically immunoreacts with mouse and rat Oprk1. It is suitable for use in a variety of assays, including WB, IP.
Specific Inquiry
WB
Figure 1 Anti-Oprk1 Antibody (VS3-FY1753) in WB.
The Kappa Opioid Receptor expression in rat Brain lysates were detected using the anti-kappa Opioid Receptor by western blot assay.
Specifications
- Immunogen
- Synthetic peptides for mouse Kappa opioid receptors
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Mouse and Rat Oprk1
- Species Reactivity
- Mouse, Rat
- Clone
- R03-2A5
- Applications
- Western Blot, Immunoprecipitation
- MW
- The calculated weight of the target protein is approximately 43 kDa, while the observed molecular weight stands at 60 kDa.
- Related Disease
- Morphine Dependence and Cocaine Dependence
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunoprecipitation: 1/20
Target
- Alternative Names
- Opioid Receptor Kappa 1; K-OR-1; KOR-1; OPRK; Kappa-Type Opioid Receptor; Opioid Receptor, Kappa 1; Opiate Receptor, Kappa-1; Kappa Opioid Receptor; KOR
- Gene ID
- 18387
- UniProt ID
- P33534
- Sequence Similarities
- Belongs to the G-protein coupled receptor 1 family.
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Disulfide bond
Glycoprotein
Lipoprotein
Palmitate
- Function
- G-protein coupled opioid receptor that functions as a receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as a receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "OPRK1"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2742z | Mouse Anti-OPRK1 Recombinant Antibody (clone 43A12) | ELISA, IHC | Mouse IgG1 |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NBD-0056-YJ-VHH | Camelid Anti-OPRK1 Recombinant Single Domain Antibody (NBD-0056-YJ-VHH) | ELISA | Camelid VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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