AbPlus™ Anti-PHGDH Magnetic Beads (VS-0724-YC510) (CAT#: VS-0724-YC510)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-PHGDH specific antibody

• Target
• PHGDH

• Immunogen
• Recombinant human PGD, aa 1-483.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known. [provided by RefSeq, Aug 2011]

• Alternative Names
• Phosphoglycerate Dehydrogenase; 2-Oxoglutarate Reductase; Malate Dehydrogenase; EC 1.1.1.95; 3-PGDH; Epididymis Secretory Protein Li 113; D-3-Phosphoglycerate Dehydrogenase; 3-Phosphoglycerate Dehydrogenase; EC 1.1.1.399; EC 1.1.1.37; HEL-S-113; EC 1.1.1;

• Gene ID
• 26227

• UniProt ID
• O43175

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