Mouse Anti-PSMC2 Recombinant Antibody (VS3-FY2846)
CAT#: VS3-FY2846
This anti-PSMC2 product is a recombinant mouse monoclonal antibody that targets for human PSMC2 protein. It cross-reacts with mouse species. The calculated molecular weight of the protein is about 48.6 kDa. This monoclonal antibody is suitable for employment in Western Blot (1/500-1/2000).
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human and Mouse PSMC2
- Species Reactivity
- Human, Mouse
- Applications
- Western Blot
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 48.6 kDa.
- Related Disease
- Retinal Melanoma and Cystic Fibrosis
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/2000
Target
- Alternative Names
- S7; MSS1; RPT1; Nbla10058
- Gene ID
- 5701
- UniProt ID
- P35998
- Sequence Similarities
- Belongs to the AAA ATPase family.
- Cellular Localization
- Cytoplasm
- Post Translation Modifications
- Monoubiquitinated by RNF181. (P35998-PRS7_HUMAN)
Phosphorylated (PubMed:28539385).
Dephosphorylated by UBLCP1 which impairs PSMC2 ATPase activity and disrupts 26S proteasome assembly (PubMed:28539385).
(P35998-PRS7_HUMAN)
Ubiquitination at Lys146, Lys34, Lys181, Lys46, Lys57, Lys210, Lys84, Lys222, Lys100, Lys110, Lys248, Lys116, Lys120, Lys267, Lys268, Lys340, Lys402, Lys407, Lys415, and Lys422 (NX_P35998 [NX_P35998-1])
Modification sites at PhosphoSitePlus (P35998)
Glycosylation from GlyGen (P35998) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- NP_002794.1
- Function
- Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.
This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "PSMC2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3094z | Mouse Anti-PSMC2 Recombinant Antibody (clone 36H10) | WB, ELISA, ICC, IF | Mouse IgG1, κ |
| MOB-1698CT | Recombinant Mouse anti-Human PSMC2 Monoclonal antibody (26) | ELISA, WB | |
| VS3-CJ914 | Mouse Anti-PSMC2 Recombinant Antibody (VS3-CJ914) | WB | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0446MZ | Chicken Anti-PSMC2 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1794 | Anti-PSMC2 Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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