Human Anti-SIGLEC15 Recombinant Antibody (clone h24A3-H2/L1) (CAT#: HPAB-AP451-YC)
Provided is a humanized antibody h24A3-H2/L1 which specifically recognizes human Siglec-15 and has an activity of inhibiting osteoclast formation. The binding activity of the antibody to the mouse Siglec-15 protein was evaluated, 31 pM.
Specific Inquiry
Subcellular Location and Protein Expression
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53509/1201_B2_5_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53509/1201_B2_5_selected.jpg
Figure 2 RNA cell line category: Cell line enriched (U-87 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000197046-SIGLEC15/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000197046-SIGLEC15/subcellular
Specifications
- Immunogen
- Purified soluble human Siglec-15 extracellular domain
- Host Species
- Human
- Derivation
- Humanized (rat/human)
- Type
- Humanized (rat/human) IgG2
- Specificity
- Human SIGLEC15
- Species Reactivity
- Human
- Clone
- h24A3-H2/L1
- Applications
- Inhib, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Sialic Acid Binding Ig Like Lectin 15; CD33 Antigen-Like 3; CD33 Molecule-Like 3; SIGLEC-15; CD33L3; Sialic Acid Binding Ig-Like Lectin 15; Sialic Acid-Binding Ig-Like Lectin 15; HsT1361
- Gene ID
- 284266
- UniProt ID
- Q6ZMC9
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone h24A3-H2/L1"
See other products for "SIGLEC15"
Select a product category from the dropdown menu below to view related products.
Please select product type
IgG Antibody Products
Humanized Antibody Products
Human Antibody Products
Chimeric Antibody Products
Mouse Antibody Products
Fab Antibody Products
ScFv Antibody Products
Non-Human Primate (NHP) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-904 | Recombinant Human Anti-human SIGLEC15 Antibody | ELISA, WB, FuncS | IgG |
| HPAB-0039-WJ | Human Anti-SIGLEC15 Recombinant Antibody (HPAB-0039-WJ) | ELISA, WB | Human IgG |
| HPAB-0040-WJ | Human Anti-SIGLEC15 Recombinant Antibody (HPAB-0040-WJ) | ELISA, WB | Humanized IgG |
| HPAB-0916-FY | Human Anti-SIGLEC15 Recombinant Antibody (HPAB-0916-FY) | ELISA | Human IgG |
| HPAB-0917-FY | Human Anti-SIGLEC15 Recombinant Antibody (HPAB-0917-FY) | ELISA | Human IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for HPAB-AP451-YC. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: ELISA, Inhib, FC
Application: WB, ELISA, Neut, FuncS
-1.png)
Application: ELISA
Application: FC
Application: ELISA, FuncS, RIA, IP, IF, IHC, IA, Block
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
