Human Anti-SIGLEC15 Recombinant Antibody (clone h24A3-H2d/L3b) (CAT#: HPAB-AP462-YC)
Provided is an antibody which specifically recognizes human Siglec-15 and has an activity of inhibiting osteoclast formation.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Subcellular Location and Protein Expression
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53509/1201_B2_5_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53509/1201_B2_5_selected.jpg
Figure 2 RNA cell line category: Cell line enriched (U-87 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000197046-SIGLEC15/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000197046-SIGLEC15/subcellular
Specifications
- Immunogen
- Purified soluble human Siglec-15 extracellular domain
- Host Species
- Human
- Derivation
- Humanized (rat/human)
- Type
- Humanized (rat/human) IgG2
- Specificity
- Human SIGLEC15
- Species Reactivity
- Human
- Clone
- h24A3-H2d/L3b
- Applications
- Inhib, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Sialic Acid Binding Ig Like Lectin 15; CD33 Antigen-Like 3; CD33 Molecule-Like 3; SIGLEC-15; CD33L3; Sialic Acid Binding Ig-Like Lectin 15; Sialic Acid-Binding Ig-Like Lectin 15; HsT1361
- Gene ID
- 284266
- UniProt ID
- Q6ZMC9
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-568CL | Human Anti-SIGLEC15 Recombinant Antibody (TAB-568CL) | ELISA | Human IgG2 |
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